Solvate and Hydrate is a piece of important information in the Pharmaceutical Industry. The definitions are available below.
What is solvate form?
When a solute crystallizes from solution, it may do so either as a pure crystal or as a solvate, in which solvent molecules are incorporated into the lattice. When the incorporated solvent is water, the solvate crystals are termed hydrates. Solvate formation, in particular hydrate formation, is a common phenomenon.
What is Drug Solvate?
Hydrates or solvates of a drug substance, similar to polymorphs, are crystal modifications of a drug substance. This characteristic of solvate formation is sometimes known as pseudomorphism.
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What is the difference between Solvate and Hydrate?
Solvation is the process of attraction and association of molecules of a solvent with molecules or ions of a solute. Hydration is the process of attraction and association of molecules of water with molecules or ions of a solute.
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